Dynamic Contrast-Enhanced MRI Perfusion Parameters as Imaging Biomarkers of Angiogenesis
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چکیده
منابع مشابه
Dynamic Contrast-Enhanced MRI Perfusion Parameters as Imaging Biomarkers of Angiogenesis
Hypoxia in the tumor microenvironment is the leading factor in angiogenesis. Angiogenesis can be identified by dynamic contrast-enhanced breast MRI (DCE MRI). Here we investigate the relationship between perfusion parameters on DCE MRI and angiogenic and prognostic factors in patients with invasive ductal carcinoma (IDC). Perfusion parameters (Ktrans, kep and ve) of 81 IDC were obtained using h...
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BACKGROUND Breast cancer is the most common malignancy and the leading cause of cancer death in women worldwide; however, early diagnosis has been difficult due to its complex pathological structure. This study evaluated the value of morphological examination in conjunction with dynamic contrast-enhanced MRI (DCE-MRI) for more precise diagnosis of breast cancer, as well as their correlation wit...
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Fig. 1 (a) Plots of Kinetic parameters (K, ve, kep, IAUC) vs. assumed baseline T1 when a true T1=800 ms with K trans = 0.5min, IAUC = 0.039 M⋅s, kep = 1.25 min , and ve = 0.4. (b) Plots of the normalized ratios (NR) of IAUC, kep, K trans and ve. True NRs are 0.77, 0.6, 0.5 and 0.125, respectively. The same true T1 (800 ms) was assumed for both preand post-treatment. Fig. 2. Effects caused by th...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2016
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0168632